SIGA Technologies gets $3 mn research grant from NIH

SIGA Technologies, Inc., a company specializing in the development of pharmaceutical agents to fight bio-warfare pathogens, has received a phase II grant of approximately $3 million from the National Institutes of Health (NIH), to continue exploring the use of ST-246 as an adjunct to the current smallpox vaccine for prevention of smallpox vaccine-related adverse events.

SIGA will evaluate the efficacy of ST-246 in preventing smallpox vaccine-related adverse events in non-human primate models of immunodeficiency and evaluate the impact of concurrent ST-246 administration on ACAM2000 vaccination efficacy in a monkeypox challenge in non-human primate models of immunodeficiency. 

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