Millipore introduces novel kit for RNA-protein binding

Millipore has launched its new Magna RIP RNA binding protein imuno precipitation kit to provide a complete solution for the entire RIP workflow. With this kit, any researcher, even those inexperienced in RNA purification, can investigate the dynamics of ribonucleoprotein assembly as it occurs inside the cell.

Cells respond to stimuli by altering gene expression, and RNA-protein complexes drive almost all processes regulating gene expression at the post-transcriptional level, including splicing, nuclear export, mRNA stability, and translation.

Therefore, understanding gene regulation depends on characterizing the changes in RNA binding in these various processes. Traditionally, RNA-protein interactions have been identified by screening libraries in yeast, bacteria, or by in vitro selection, all confounded by system limitations, biases, or artifacts. In contrast, data obtained from RIP shows increased biological relevance, enabling researchers to achieve their goals more quickly.